Overall, MVMs do not appear to reliably reduce the risk of chronic diseases when people choose to take these products for up to a decade or when studies randomize people to take them as part of a clinical trial. In 2021, after another review of studies published since 2013, the USPSTF concluded that the evidence is still insufficient to weigh the benefits and harms of MVM use to prevent CVD or cancer . The American Institute for Cancer Research recommends against taking dietary supplements for cancer prevention because supplements do not provide the same benefits as eating whole foods . Similarly, the American Heart Association advises against the use of MVMs to prevent CVD because scientific studies have found them to be of no value for this purpose . Older adults are susceptible to vitamin and mineral deficiencies for a variety of reasons and have an increased demand for many of these micronutrients. Multivitamin/multimineral supplement offer a simple way for adults to improve nutrient intake, but their ability to measurably affect micronutrient status in older adults has never been explored.
This study intends to recruit healthy, non-smoking men aged 65 years or older. After meeting entry criteria, subjects will be required to restrict the use of supplements and/or fortified foods. Two months after these restrictions have begun, subjects will come to the clinical research center to take cognitive tests, undergo activity monitoring, provide blood samples for nutrition testing, and take food frequency questionnaires. Subjects will then be randomized into one of two groups - one consuming a multivitamin/multimineral supplement ; another consuming an inert placebo tablet. After this period, subjects will return to the clinical research center and repeat cognitive tests, activity monitor, blood sampling, and food frequency questionnaires. The investigators expect that results of this study will add to the general understanding if multivitamin/multimineral formulas can improve nutrition status of older adults, and therefore have the capacity of altering markers of health.
Furthermore, investigators define MVMs differently in their studies to evaluate the potential health effects of these products. One team of researchers categorized MVMs more ambiguously as "stress-tab-type," "therapeutic type," and "one-a-day type," so these products probably included MVs as well . Another team defined MVMs as "full-spectrum" products providing all 12 vitamins plus 10 minerals . Some published reports of studies of dietary supplements use the generic term "multivitamins" to include products with and without minerals.
Various government surveys of dietary supplements and popular food-frequency questionnaires also define MVs and MVMs differently, include different examples, or ask about different products. With our scientific heritage, we provide you with tried and trusted products. Smaller than Centrum Women, this complete multivitamin provides daily support for your immune system with higher levels of vitamin C and zinc than Centrum Women.
A daily multivitamin formulated for adults 50+ to help promote heart health, brain function, and eye health. Older adults are at increased risk of various chronic diseases, in which inadequate levels of vitamins and minerals may play a significant role, including cardiovascular disease, Alzheimer's disease, liver disease, and cancer. Most adults in the United States do not meet the Recommended Dietary Allowance or Adequate Intake of many vitamins and nutritionally-essential minerals from diet alone, including vitamins A, C, D, E and K, calcium, magnesium, and potassium. Older adults are particularly susceptible to micronutrient inadequacies because of limited absorption, increased requirements, or - in the case of vitamin D - decreased synthetic capacity in the skin.
Thus, there is a strong rationale for supplementing the diets of older adults with a multivitamin/multimineral supplement, such as Centrum® Silver®. However, little is currently known about the bioavailability of the Centrum® Silver® formula in this age demographic. One of the largest prospective studies of MVM use was the Women's Health Initiative, which evaluated the health of 161,808 postmenopausal women aged 50–79 years and their risk factors for cancer, heart disease, and osteoporosis.
A total of 41.5% of the women took an MVM (containing 20–30 vitamins and minerals in amounts not exceeding the RDAs), an MV (10 or more vitamins in amounts of 100% or more of the RDA), or a "stress multisupplement" at least once a week. Investigators who followed a multiethnic cohort of 182,099 men and women aged 45–75 years living in Hawaii and California for an average 11 years found similar results . Approximately 48% of the men and 52% of the women in this study reported taking an MV or MVM. Besides that, people who skimp on servings from one or more food groups and eliminate certain foods, such as gluten from their diets, can also benefit from dietary supplements. Even women in their childbearing years and people over 50 that may be at risk for vitamin and mineral deficiencies are also recommended to consume good multivitamins such as Centrum Multivitamins. These multivitamins can fill gaps in nutrient intake that could result in chronic conditions, including osteoporosis, birth defects, anemia, and others.
Therefore, this study seeks to recruit men who are in generally good health, 65 years of age or older, to assess their vitamin and mineral status before and after six months of supplementation with Centrum® Silver®. The investigators hypothesize that consuming multivitamin/multimineral supplements everyday will result in measurable increases in the status of one or more vitamins or minerals in the body. Concentrations of several vitamins and minerals in blood samples will be performed, along with a general assessment of micronutrient status in white blood cells .
Centrum® Silver® supplementation may or may not have any effect on these secondary outcomes, when compared to a placebo, unless there are measurable changes in the primary outcomes. Taking a basic MVM that provides nutrients in amounts that are approximately the same as recommended intakes should be safe for healthy people. Studies of MVM users reveal no adverse effects, except that both treatment and placebo groups in some studies experienced some minor gastrointestinal issues . However, individuals who take MVMs and other supplements and who consume fortified foods and beverages might obtain some nutrients in amounts exceeding the UL, increasing the possibility of adverse effects . Excess intakes can also be a concern for people taking MVMs that contain some vitamins or minerals in amounts approaching or exceeding the UL. One well-known trial of the impact of MVMs on both chronic disease risk and mortality used combinations of antioxidant nutrients.
After 7.5 years of use, the supplements lowered total cancer incidence by 31% and all-cause mortality rates by 37% in men but not women. Other RCTs have evaluated the effects of MVMs on outcomes in individuals with a range of chronic diseases. The supplement did not reduce incidence or mortality rates for esophageal cancer or the rate of mortality from any cause. A cross-sectional analysis of a nationally representative sample of 1,003 pregnant U.S. people aged 20 to 40 years from the 2001–2014 NHANES found that many consumed less than recommended amounts of many nutrients from diet alone .
Among the 69.8% who took a dietary supplement , the risk of inadequate intakes of many nutrients was lower. For example, 27.7% had inadequate intakes of vitamin A from foods alone, but this rate dropped to 15.5% when supplements were included. However, supplement use increased the proportion of pregnant people with some intakes of iron (27.9%) and folic acid (33.4%) above the UL. Get key nutrients for healthy aging with Centrum Silver Women. Over time, women's nutritional requirements can change, which may require an adjustment to your diet.
Centrum Silver Women is a multivitamin supplement specially crafted to balance essential vitamins and minerals for women 50+. One tablet daily responds to your body's needs for healthy aging. Centrum Select 50+ 30 Tablets, from the best loved vitamin brand in South Africa, is specifically formulated with carefully selected vitamins and minerals for adults aged 50 and over.
It provides them with a blend of multivitamins to complement their intake of healthy foods and the active lifestyles they lead. Basic MVMs contain both vitamins and minerals, most in amounts that do not exceed the DVs. However, MVMs often have small amounts of certain nutrients, such as calcium, magnesium, and potassium, so supplement users should check product labels. When choosing an MVM product, consumers should consider taking a product designed for people of their age, sex, and life stage (e.g., pregnancy). MVMs for "senior" men and women, for example, often contain little or no iron and more calcium, vitamin D, and vitamin B12 than MVMs for younger adults . Prenatal supplements generally provide no vitamin A in the form of retinol, and most children's MVMs provide age-appropriate amounts of nutrients.
Vitamins are needed for the body to function well.This vitamin/mineral combination contains high levels of B vitamins (such as folic acid, niacin, B-1, B-2, B-6, and B-12) and vitamin C. It also contains other vitamins and minerals such as zinc. This medication does not contain iron and has only a small amount of calcium. It should not be used to treat "iron-poor" blood or to prevent osteoporosis. If you eat a well-balanced diet and don't have any medical conditions, you may not get many benefits from vitamin supplements or mineral supplements. However, many seniors find they don't get enough nutrition whether it's due to health conditions such as blood sugar problems, side effects of medications, or a decrease in bone health.
Visit your doctor to determine if vitamin supplements are right for you. Centrum Adult is the perfect multivitamin that is formulated to support busy adults that require help in maintaining a balanced diet and hectic work schedules. With high levels of vitamin D, Centrum Adults has more vitamin D3, a preferred form of vitamin D. Key nutrients like iron, Vitamin B, C, E, Beta-Carotene, and Zinc can help support your energy, immunity, and metabolism. There are 30 key nutrients important for your body to help fill nutritional gaps in one capsule; Centrum Adult is your perfect health companion. Epidemiological studies and recent clinical trials have shown that use of multivitamin/mineral supplements has beneficial effects on disease risk in men, including those of advanced age.
It is assumed that these benefits of multivitamin/mineral supplements are achieved through changes in nutrition status. However, it has never been documented if there are concomitant changes in micronutrient levels in individuals who consume these supplements. Furthermore, changes in nutritional status in older individuals taking multivitamin/multimineral supplements are a subject that has yet to be explored. For many older adults, aging gracefully, staying active, and maintaining health are key goals.
As the years go by, it can become more difficult to get the vitamins and minerals we need to stay healthy and active. Fortunately, dietary supplements can fill the gaps that make it harder to get nutrients from food. Although health experts favor food for meeting vitamin and mineral needs, many people cannot fulfill the required daily nutrients. Therefore, vitamins and mineral supplements now play a new role in helping support our daily diet.
Keep in mind that they are not substitutes for a balanced eating plan. You can't take a vitamin C tablet and not eat fruits or vegetables at all; tablets are only supplements. That said, over-consuming vitamins may also bring more harm than good. So, it is important to learn about your daily dietary needs and select suitable supplements that will complement your dietary needs. Some evidence from RCTs has focused on the use of MVMs to reduce the risk of various chronic diseases. Use of MVs and MVMs (products containing three or more vitamins and/or minerals in amounts below the ULs and no herbs) did not reduce the risk of any chronic disease.
In Canada, almost all prenatal MVM supplements provide 1,000 mcg/day of folic acid. Even in the United States, the amount of folic acid in prenatal MVM supplements is typically 800 or 1,000 mcg, which is much higher than the recommended amount to reduce the risk of neural tube defects in babies . The DGA does not mention MVMs, but it does recommend that Americans choose healthy, nutrient-dense food and beverages. The DGA lists nutrients of special public health concern in American diets, such as calcium, potassium, dietary fiber, and vitamin D in both adults and children.
Iron is also a nutrient of public health concern for infants ages 6–11 months who are fed primarily human milk and do not consume enough iron from complementary foods, adolescent females, and people who are pregnant. Depending on their formulations, MVMs can help individuals obtain adequate amounts of these nutrients, except for potassium and dietary fiber. The American College of Obstetricians and Gynecologists recommends that pregnant people take a daily "prenatal vitamin" .
Acknowledging that most healthcare providers recommend that pregnant people take a daily prenatal MVM, the DGA states that this practice may be necessary to meet the needs for folate or folic acid, iron, iodine, and vitamin D during pregnancy . The report recommends that people following a vegetarian or vegan diet consult their healthcare provider about whether they need supplementation with iron, vitamin B12, and other nutrients (e.g., choline, iodine, EPA, and DHA). The World Health Organization recommends iron and folic acid supplementation throughout pregnancy . Most studies of the potential value of MVMs to enhance health and prevent disease have been observational and compared individuals who chose to take MVM supplements with others who did not take supplements. Because people with healthier diets and lifestyles are more likely to use dietary supplements, attributing health benefits that are distinct from the benefits of healthy behaviors to the use of supplements is difficult .
Can A 20 Year Old Take Centrum Silver Some studies have suggested potential health benefits or harms from the use of MVMs, but others have found none. Participants in these studies used a wide variety of MVMs containing different combinations and amounts of nutrients. Multivitamins, including Centrum products, are generally safe. However, most people don't need to take multivitamins or dietary supplements.
Any multivitamin can be toxic when consumed in excessive quantities. If you choose to consume a dietary supplement, make sure you only consume the recommended amount. Remember that it is best to get your vitamins and minerals from healthy foods.
Maintain a well-balanced diet and follow any dietary guidelines as directed by your doctor. B vitamins, including folic acid, are naturally found in leafy greens and other vegetables, and citrus fruits. You will also find folic acid in enriched grains such as bread, pasta and cereal.
Centrum MultiGummies are multivitamins containing several of the essential vitamins and minerals your body needs. Therefore, these products should not be taken with any other multivitamin products. We recommend always checking with your healthcare professional about the best regimen to follow for your dietary supplement needs.
The FNB advises people older than 50 years to obtain recommended amounts of vitamin B12, mainly from fortified foods or dietary supplements. Adults in this age group might not be able to absorb enough of the protein-bound, naturally occurring vitamin B12 in food because gastric acidity tends to decline and atrophic gastritis tends to become more common with age . The DGA also recommends obtaining recommended amounts of vitamin B12 primarily from fortified foods or dietary supplements, but only for people ages 60 and older.
The DGA adds that the use of some medications can decrease absorption of vitamin B12 in foods . One meta-analysis of 21 RCTs investigated whether daily use of MVs and MVMs for at least 1 year affected mortality risk . The studies included a total of 91,074 healthy adults taking the MVs or MVMs for an average of 43 months, and the investigators reported 8,794 deaths. The products provided an average of 14 nutrients, although the products with 3 nutrients in 5 trials did not contain a mineral. The use of MVs or MVMs had no effect on all-cause mortality or on mortality due to CVD or cancer.
Centrum Silver Advance is used for the treatment and prevention of vitamin and mineral deficiencies in adults aged 50 years and above. With Centrum Silver Advance the patient can be assured that he/she will get up-to-date nutritional support. As scientists discover more about the association between good health and vitamins and minerals, the patient can feel confident that Centrum incorporates the latest advances in nutrition. Getting older doesn't mean you have to slow down, but it may mean you need to adjust your nutrient levels to respond to your body's changing needs. Centrum Silver Adults is specially crafted for healthy aging in your 50s and beyond.
It's made with high-quality ingredients and all the essential vitamins and minerals to keep your heart+§, brain°, and eyes‡ healthy and protected. If you're a healthy adult, taking a multivitamin won't lower your risk of heart attack, stroke or death from cardiovascular disease. Preventive Services Task Force concluded that there is insufficient evidence to support any benefit from vitamin and mineral supplementation for the prevention of cancer or cardiovascular disease. A daily multivitamin can help ensure you get the nutritional elements you need to live an active, healthy lifestyle well into your golden years. These supplements contain a blend of vitamins that most seniors don't receive enough of. They include vitamin E, vitamin K, vitamin A, calcium, vitamin D, folic acid, and potassium.
Other formulations include lycopene, lutein, and probiotics. As we get older, many factors make it harder to get the vitamins and minerals we need. Often, as we age, we cook less than we used to, especially if the house is less full than it once was.
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